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This randomized clinical trial examines the distribution and prognosis of residual cancer burden across high-risk phenotypic subtypes of breast cancer and by different treatment groups.

This was a multicenter cohort study of pancreatic cancer family registries in the US and Canada examines age-specific penetrance of pancreatic cancer in individuals with pathogenic variants in the ATM gene.

This single-arm diagnostic imaging trial assesses the accuracy of ⁶⁸Ga-PSMA-11 positron emission tomographic imaging in detecting pelvic nodal metastases compared with histopathology.

This phase 2 nonrandomized controlled trial investigates the use of carfilzomib, lenalidomide, and dexamethasone followed by lenalidomide maintenance therapy for the prevention of symptomatic multiple myeloma in patients with high-risk smoldering myeloma.

This cohort study examines changes in late mortality and life expectancy in individuals who received blood or bone marrow transplantation from 1974 to 2014.

This review summarizes clinical aspects related to the application of neoadjuvant endocrine therapy in the treatment of hormone receptor–positive/ERBB2-negative breast cancer.

This Viewpoint discusses how biases associated with selective inference and multiple testing can potentially invalidate the conclusions of studies using routinely collected health data.

This randomized clinical trial compares ensartinib with crizotinib among patients with advanced anaplastic lymphoma kinase (ALK)–positive non–small cell lung cancer (NSCLC) who had not received prior treatment with an ALK inhibitor.

This age-period-cohort analysis examines whether human papillomavirus vaccination will alter the incidence of oropharynx cancer through 2045.

This review describes the registry efforts made during the COVID-19 pandemic with the aim of investigating and sharing information about the history, risk factors, and outcomes of patients with COVID-19 and cancer.

A 33-year-old woman with a history of hereditary bilateral retinoblastoma as an infant presents with 1 week of right lower extremity swelling. What is your diagnosis?

This Viewpoint describes perceived benefits and risks of open notes in cancer treatment and their effects on the patient-physician relationship.