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Sep 2011

Anterior Chamber and Vitreous Concordance in Endophthalmitis

Author Affiliations

Author Affiliations: L.V. Prasad Eye Institute, Hyderabad, India.

Arch Ophthalmol. 2011;129(9):1243-1244. doi:10.1001/archophthalmol.2011.235

We read the article by Almeida et al1 with interest. There are a few overlooked issues that we would like to highlight.

The authors have attempted to examine the relationship between anterior chamber sterilization and vitreous positivity rate in endophthalmitis, with implications for postcataract surgery endophthalmitis. However, the sample selected by them includes a heterogenous population of both endogenous and exogenous cases of endophthalmitis. The mechanism of entry of microorganisms is specific in the case of cataract surgery, as opposed to posttraumatic or endogenous cases. Inclusion of these cases confounds the data, as the microbiological profile, load, and route of entry is not comparable. Analysis of this diverse population and interpretation of the results for postcataract surgery endophthalmitis would be extrapolation beyond the data.