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Nov 2011

Chloroquine and Hydroxychloroquine Toxicity

Author Affiliations

Author Affiliations: Department of Ophthalmology, St. James University Hospital, Leeds, England.

Arch Ophthalmol. 2011;129(11):1506-1507. doi:10.1001/archophthalmol.2011.321

We have read with interest the article on retinal toxic reaction secondary to chloroquine and hydroxychloroquine use, finding it to be both comprehensive and informative.1 Of particular interest were the data on drug dosage calculation for actual and lean body weight and the use of novel methods of imaging to identify signs of a toxic reaction. The article prompted us to review our patients with a diagnosis of a chloroquine or hydroxychloroquine toxic reaction and the relevant risk factors in these cases (Table).

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