Dr Saraiya and colleagues describe a patient with bilateral idiopathic chronic iridocyclitis with multifocal choroiditis and persistent cystoid macular edema despite maximally tolerated systemic immunosuppression. In addition, the patient, a known “steroid responder,” was being treated with topical prednisone acetate ophthalmic suspension (Pred Forte; Allergan, Irvine, California) twice daily and topical brimonidine tartrate–timolol maleate twice daily in both eyes. The patient received dexamethasone intravitreal implants (Ozurdex; Allergan, Irvine, California) in the left eye and then in the right eye 3 weeks later, with rapid resolution of cystoid macular edema. Within 2 months after the initial injection, the patient developed elevated intraocular pressure (IOP) in both eyes that continues despite receiving 4 topical IOP-lowering medications and oral methazolamide.
Lowder C, Belfort R, Lightman S, et al. A Report of High Intraocular Pressure With the Dexamethasone Intravitreal Implant—Reply. Arch Ophthalmol. 2011;129(12):1638–1640. doi:10.1001/archophthalmol.2011.356
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: