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April 2013

No, Not More Talk About Duane Syndrome

Author Affiliations

Author Affiliation: Department of Ophthalmology, University of California, San Francisco, School of Medicine.

JAMA Ophthalmol. 2013;131(4):522-524. doi:10.1001/jamaophthalmol.2013.1638

Duane syndrome is a well-defined congenital ocular motor abnormality that, in its most usual form, is characterized by (1) a large duction deficit (usually abduction) accompanied by (2) a disproportionately small horizontal deviation in primary gaze that is compensated for by (3) a slight face turn that acts to ensure that (4) normal binocularity is maintained; (5) amblyopia is uncommon and usually associated with anisometropia.1,2 Other variable features include a mild to moderate limitation of adduction, palpebral narrowing on adduction, and vertical upshoots or downshoots in adduction. Duane syndrome is usually not associated with other ocular or systemic abnormalities, occurs more commonly in the left eye, and is more frequently seen in women than in men.1,2 Familial occurrences are infrequent. In the majority of cases, no specific ophthalmological treatment is required.2