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April 2013

Need for Revised Screening Protocol for Early Detection of Retinopathy of Prematurity in Infants Born Before 25 Weeks

Author Affiliations

Author Affiliations: Departments of Surgery (Dr Kishore) and Neonatology (Dr Macwan), University of Illinois College of Medicine, Peoria.

JAMA Ophthalmol. 2013;131(4):546-547. doi:10.1001/jamaophthalmol.2013.1417

We read the article by Hu et al1 with interest and congratulate the authors for an excellent study. We were struck by the early gestational age (GA) and the significant standard deviation in GA and chronological age at treatment of ROP for infants in the study (mean [SD], 25.0 [2.8] and 8.9 [2.6] weeks, respectively). It is possible that a GA of 25 weeks or less might further predispose these infants to an adverse outcome by delay in diagnosis as a result of adherence to a current screening protocol that calls for initial screening examination beginning at 4 weeks' chronological age or 31 weeks' PMA, whichever is later.2

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