Author Affiliations: Department of Ophthalmology, University of Chicago (Dr Blair) and Department of Ophthalmology, University of Illinois at Chicago (Drs Blair and Shapiro), Chicago, and Retina Consultants, Ltd, Des Plaines (Drs Blair and Shapiro).
We thank Mireskandari and coworkers for interest in our article.1 Although ROP recurrences after the 54-week BEAT-ROP2 end point were predicted,3,4 our aims were to describe novel reactivation patterns and progression to RD. We described reactivation of persistent ROP, which had not regressed sufficiently after initial treatment, and ROP recurrence after initial regression. We described posterior and anterior reactivation patterns. We reported that no eye treated with laser for reactivation progressed to RD. We suggested close follow-up until either retina vascular termination reaches its normal location near the ora serrata5 or laser treatment is performed. We acknowledge our study to be small, retrospective, and subject to referral bias.
Blair MP, Shapiro MJ. Need for Revised Screening Protocol for Early Detection of Retinopathy of Prematurity in Infants Born Before 25 Weeks—Reply. JAMA Ophthalmol. 2013;131(4):546–547. doi:10.1001/jamaophthalmol.2013.35
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