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Case Report/Case Series
August 2013

Intrachoroidal Cavitation in North Carolina Macular Dystrophy

Author Affiliations
  • 1Department of Ophthalmology, Vanderbilt Eye Institute, Nashville, Tennessee
JAMA Ophthalmol. 2013;131(8):1073-1076. doi:10.1001/jamaophthalmol.2013.1598

North Carolina macular dystrophy (NCMD) is an autosomal dominantly inherited condition with 3 phenotypic grades.1 Grade 1 has yellow or white drusenlike deposits. Grade 2 features confluent drusen, pigmentary changes, retinal pigment epithelial (RPE) atrophy, or subretinal scarring. Grade 3 is described as a macular staphyloma, coloboma, or caldera with hyperpigmentation and subretinal fibrosis. Different grades and expressivity may be seen within one family, and the etiology is unknown.2

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