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In the Small Case Series article titled “Novel Mutation in BEST1 Associated With Retinoschisis,” published online on April 9, 2013, and in the June 2013 issue of JAMA Ophthalmology (2013;131:794-798. doi:10.1001/jamaophthalmol.2013.2047), a phenotypically significant polymorphism in the initial sequencing of the BEST1 gene was identified: (Glu213Lys). However, a second potentially phenotypically significant mutation (Pro404 del1cctC) was omitted. Thus, the sentences, “In our siblings, 5 separate polymorphisms were identified in sequencing BEST1. Only 1 of these was deemed phenotypically significant: a single guanine to adenosine substitution resulting in a Glu213Lys amino acid change.” should have read as, “In our siblings, 6 separate polymorphisms were identified in sequencing BEST1. Only 2 of these were deemed phenotypically significant: a single guanine to adenosine substitution resulting in a Glu213Lys amino acid change and a frameshift mutation at amino acid position 404 (Pro404 del1cctC).” This article was corrected online.
Omitted Mutation. JAMA Ophthalmol. 2013;131(9):1249. doi:10.1001/jamaophthalmol.2013.5755
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