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Comment & Response
November 2013

Fundus Autofluorescence Is Not the Best Early Screen for Hydroxychloroquine Toxicity

Author Affiliations
  • 1Byers Eye Institute at Stanford, Palo Alto, California
JAMA Ophthalmol. 2013;131(11):1487-1488. doi:10.1001/jamaophthalmol.2013.4835

To the Editor I was pleased to see pictures of hydroxychloroquine toxicity in the recent Ophthalmic Images,1 as a reminder that the problem still exists. However, some readers may draw an erroneous impression from the caption, which suggests that fundus autofluorescence may “be useful to determine whether patients with macular pigmentary change may continue using hydroxychloroquine.”