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November 2014

Optic Disc Pit Maculopathy Recurring in the Absence of Vitreous Gel

Author Affiliations
  • 1Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston
JAMA Ophthalmol. 2014;132(11):1375-1376. doi:10.1001/jamaophthalmol.2014.2054

Optic disc pit (ODP) is a rare congenital cavitation in the optic nerve head frequently associated with serous detachments of the macula, ODP maculopathy (ODP-M), and subsequent visual decline.1 Optic disc pit maculopathy is preceded by development of a schisis cavity due to accumulation of intraretinal fluid from the ODP. The source of the fluid remains controversial and 4 mechanisms have been hypothesized: (1) fluid from the vitreous cavity2; (2) cerebrospinal fluid originating from the subarachnoid space3; (3) fluid originating from the orbital space surrounding the dura1; and (4) fluid from leaky blood vessels at the pit base.1