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Ophthalmic Images
July 9, 2015

Moniliform Blepharosis of Lipoid Proteinosis

Author Affiliations
  • 1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada
  • 2Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
  • 3The Hospital for Sick Children, Toronto, Ontario, Canada
JAMA Ophthalmol. 2015;133(7):e150688. doi:10.1001/jamaophthalmol.2015.0688

Two brothers (both younger than 13 years) were evaluated for eyelid margin lesions (Figure). Lesions were present on all 4 lids in both boys. The lesions were itchy and did not respond to steroid or antibiotic therapy. Demodex test results were negative and tea tree oil was ineffective. A full-thickness eyelid biopsy showed dense deposits of eosinophilic hyaline material in the dermis. The lesions are examples of the moniliform blepharosis of lipoid proteinosis.

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