Minocycline hydrochloride is a synthetic tetracycline antibiotic used to treat conditions such as acne vulgaris, rosacea, rheumatoid arthritis, and bullous pemphigoid.1 Tetracycline antibiotics, and minocycline in particular, can cause a blue-black or slate-gray discoloration of tissues including the skin, nails, teeth, oral mucosa, thyroid, and bones.2 There are a few reported cases of minocycline-related ocular pigmentation, including reports of pigmentation of the sclera3-5 and conjunctiva4,6 and a single reported case of retinal pigmentation.4