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January 2016

Periorbital Necrotizing Fasciitis Following Dexamethasone Intravitreal Implant Injection

Author Affiliations
  • 1Department of Ophthalmology, Strasbourg University Hospital, Fédération de Médecine Translationnelle de Strasbourg, University of Strasbourg, Strasbourg, France
JAMA Ophthalmol. 2016;134(1):110-111. doi:10.1001/jamaophthalmol.2015.4351

Periorbital necrotizing fasciitis (PNF) is a life-threatening bacterial infection involving superficial and deep fascia with secondary necrosis of overlying skin. There are multiple reports of different inciting events such as local blunt trauma or penetrating injuries.1 Iatrogenic PNF has been reported after blepharoplasties, dacryocystorhinostomies, and retrobulbar injections.2,3 We report a case of PNF after a dexamethasone intravitreal implant injection for diabetic macular edema.

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