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Invited Commentary
March 2016

What Is Chronic or Persistent Diabetic Macular Edema and How Should It Be Treated?

Author Affiliations
  • 1Washington University School of Medicine, St Louis, Missouri
JAMA Ophthalmol. 2016;134(3):285-286. doi:10.1001/jamaophthalmol.2015.5469

Diabetes mellitus can cause significant tissue damage as manifested by nephropathy, neuropathy, and, in the eye, diabetic retinopathy. Vision loss in patients with diabetes is often associated with diabetic macular edema (DME). Because 3 different modalities of therapy, including focal laser photocoagulation, intravitreal anti–vascular endothelial growth factor (VEGF) agents, and corticosteroids, have been approved by regulatory authorities worldwide, physicians and patients are in a new era with diverse options to prevent moderate and severe vision loss from DME.1-5