[Skip to Navigation]
JAMA Ophthalmology Clinical Challenge
July 2016

Management of Retinal Whitening With Vitritis

Author Affiliations
  • 1Associated Retinal Consultants, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan
JAMA Ophthalmol. 2016;134(7):835-836. doi:10.1001/jamaophthalmol.2015.5359

A woman in her 80s was seen with blurred vision in the right eye for 1 week. Her history consisted of non–small cell lung cancer treated with wedge resection 2 years prior, and she had been receiving chemotherapy until 1 year previously. She was declared free of cancer 6 months earlier based on systemic surveillance. Visual acuity was 20/80 OD and 20/20 OS. Intraocular pressures were 19 mm Hg OU. Biomicroscopy showed trace anterior chamber cells in the right eye with mild vitritis. Fundus examination demonstrated parafoveal whitening with hemorrhage and focal aggregations (Figure, A). The lesion stained on fluorescein angiography (Figure, B). There was no evidence of disc edema or vasculitis. Optical coherence tomography showed disorganization of the retina.