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Ophthalmic Images
January 12, 2017

Treatments for Retinoblastoma Then and Now

Author Affiliations
  • 1Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania
JAMA Ophthalmol. 2017;135(1):e164652. doi:10.1001/jamaophthalmol.2016.4652

Intravenous, intra-arterial, and intravitreous chemotherapy are modern treatments for retinoblastoma that can achieve favorable tumor control and globe salvage without facial disfigurement that may follow external beam radiotherapy.1-4 A girl in her second year of life with bilateral germline-mutation retinoblastoma received intravenous chemotherapy and subsequent intra-arterial and intravitreous chemotherapy with complete tumor control.