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March 2017

Zika-Related Bilateral Hypertensive Anterior Acute Uveitis

Author Affiliations
  • 1Department of Ophthalmology, University Hospital of Martinique, France, French West Indies
  • 2Department of Virology, University Hospital of Martinique, France, French West Indies

Copyright 2017 American Medical Association. All Rights Reserved.

JAMA Ophthalmol. 2017;135(3):284-285. doi:10.1001/jamaophthalmol.2016.5689

The Zika virus (ZIKV) induces flu-like symptoms with rash and conjunctival redness in 20% of patients. In Martinique, a Caribbean island with a population of 390 000, the 2015 ZIKV outbreak has caused more than 33 000 cases.1 First ZIKV ocular manifestations were reported in Brazilian newborns with congenital Zika syndrome whose mothers were infected during pregnancy. One-third of the babies had congenital lesions of retina, choroid, and optic nerves.2 None showed active intraocular inflammation.3 We report 2 cases of bilateral hypertensive anterior uveitis in patients with active ZIKV infection.