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Photo Essay
September 1998

Capillary Nonperfusion of the Retina in Diabetes Mellitus

Arch Ophthalmol. 1998;116(9):1260-1261. doi:10.1001/archopht.116.9.1260

A 34-YEAR-OLD man complained of gradual decreased vision in the right eye of 2 years' duration. He denied symptoms in his left eye. His medical history was significant for non–insulin-dependent diabetes mellitus for 8 years. He denied hypertension, hemoglobinopathies, or other systemic or vascular disease.

Visual acuity was counting fingers OD, 20/30 OS. Slitlamp examination revealed iris neovascularization in the right eye. Funduscopic examination of the right and left eyes revealed clear media, scattered dot and blot hemorrhages, cotton-wool spots, bilateral neovascularization of the disc, markedly sheathed retinal arterioles, venous beading, and featureless peripheral retina (Figure 1). A fundus map1 of the fluorescein angiography showed bilateral neovascularization of the disc with severe capillary nonperfusion in both eyes everywhere but in the peripapillary region and nasal macula (Figure 2).