Thirty-five years ago, the concept of ocular hypertension led to intensive
efforts to find tests that might predict which patients would develop glaucomatous
visual field loss. One of these tests was the genetically inherited ability
to taste the compound phenylthiocarbamide (PTC). Nontasters are considered
to be homozygous for a single recessive gene.1
Extensive literature exists on the ability of various populations to taste
this compound and on diseases associated with this trait.
Robert Ritch, Jeffrey M. Liebmann, Rabia Gürses-Özden, Ahmed Emarah. Phenylthiocarbamide Taste Testing in Patients With Pigmentary Glaucoma. Arch Ophthalmol. 2001;119(2):309–310. doi: