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Comment & Response
November 2017

Risk of Intraocular Bleeding and the New Anticoagulants: Not Such a Big Effect

Author Affiliations
  • 1Moorfields Eye Hospital NHS Foundation Trust, London, England
  • 2London School of Hygiene and Tropical Medicine and Institute of Ophthalmology, University College London, London, England
  • 3Clinical Research Department, London School of Hygiene and Tropical Medicine, London, England
JAMA Ophthalmol. 2017;135(11):1281. doi:10.1001/jamaophthalmol.2017.4021

To the Editor We read with interest the systematic review of the risk of intraocular bleeding with novel oral anticoagulants compared with warfarin. Sun and colleagues1 identified a modest relative risk reduction in intraocular bleeding with novel anticoagulants compared with warfarin in a meta-analysis of 12 randomized clinical trials with more than 100 000 patients.

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