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JAMA Ophthalmology Clinical Challenge
February 2018

New-Onset Floaters as Presenting Symptom

Author Affiliations
  • 1Department of Ophthalmology, Saint Louis University Eye Institute, St Louis, Missouri
JAMA Ophthalmol. 2018;136(2):211-212. doi:10.1001/jamaophthalmol.2017.3504

A patient in her 50s with a history of type 2 diabetes and mild bilateral nonproliferative diabetic retinopathy presented with new-onset floaters in both eyes but no blurry vision, eye pain, or photopsia. This patient was recently discharged from the hospital for West Nile virus (WNV) encephalitis (confirmed seropositive for IgM and IgG antibodies against WNV). Polymerase chain reaction analyses detected no DNA for Epstein-Barr virus, BK virus, cytomegalovirus, or herpes simplex virus types 1 and 2. Neither HIV antibody nor antigen was detected. Cerebrospinal fluid culture analysis findings were normal. She received supportive treatment and made a full recovery.

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