Hans Hoerauf et al1 present an interesting
case of vision loss, possibly associated with choroidal ischemia following
treatment with interferon-alfa-2b for metastatic renal cell carcinoma. I'm
not certain, however, that the published photographs, particularly the fluorescein
angiograms, support the conclusion of choroidal ischemia. Although the authors
comment that ocular symptoms were noted roughly 1 month after beginning interferon
treatment, they do not specify what those symptoms were. Interestingly, the
visual acuity was 20/20 OU. In addition, if fundus photographs and fluorescein
angiography were obtained when symptoms first occurred, it would be helpful
to know the results of those examinations.
Kinyoun JL. Fluorescein Angiograms Do Not Support Choroidal Ischemia. Arch Ophthalmol. 2001;119(4):621–622. doi:
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