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Comment & Response
February 2018

Role of Maternal Race on Algorithms Predicting Retinopathy of Prematurity

Author Affiliations
  • 1Barts & The London School of Medicine and Dentistry, Whitechapel, London
JAMA Ophthalmol. 2018;136(2):221. doi:10.1001/jamaophthalmol.2017.5689

To the Editor The article by Binenbaum et al1 is a valuable addition to the literature in that it is a large multicenter study evaluating the Children’s Hospital of Philadelphia Retinopathy of Prematurity model (CHOP ROP) in a multiethnic cohort.

Given that maternal race/ethnicity is considered to be a predictor for the development of ROP that requires treatment,2,3 it would be interesting to know whether the sensitivity of CHOP ROP varied significantly by maternal race/ethnicity in this study. Similarly, seeing as the authors eluded to the fact that studies that validated algorithms, such as WINROP, demonstrated 100% in single-center studies but that this was not replicated on a multicenter level, a breakdown of sensitivities across each of the centers may be insightful. If there is any difference, a subsequent analysis of the differences in maternal race/ethnicity at each center may be valuable given that communities of similar races/ethnicities may congregate in one area that is served by a center.

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