Paecilomyces lilacinus, an uncommon cause of
exogenous endophthalmitis, presents a challenging management problem since
the organism is usually resistant to amphotericin B, the most commonly employed
intravitreal antifungal, and natamycin, a frequently employed topical antifungal.
The organism is sensitive to miconazole nitrate, ketoconazole, and, in some
cases, fluconazole. We report 4 cases of endophthalmitis caused by P lilacinus and discuss treatment options.
Ingrid U. Scott, Harry W. Flynn, Darlene Miller, James W. Speights, Robert C. Snip, Roy D. Brod. Exogenous Endophthalmitis Caused by Amphotericin B–Resistant Paecilomyces lilacinus: Treatment Options and Visual Outcomes. Arch Ophthalmol. 2001;119(6):916–919. doi: