Asteroid hyalosis is a degenerative change of the vitreous that consists of yellow-white opacities that reflect light and impede the quality of color fundus photography (CFP).1 Eyes that have retinal disease along with dense asteroid hyalosis usually need spectral-domain optical coherence tomography (SD-OCT) or fluorescein angiography (FA) for adequate assessment of the retina.2,3 Although SD-OCT and FA do provide information about anatomy of retinal layers and retinal blood vessels, they do not provide information about the spatial distribution of retinal lesions.
Saurabh K, Roy R, Chowdhury M. Efficacy of Multicolor Imaging in Patients With Asteroid HyalosisSeeing the Unseen. JAMA Ophthalmol. 2018;136(4):446–447. doi:10.1001/jamaophthalmol.2018.0026
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