To the Editor The article titled “Effect of Dietary Supplementation With Lutein, Zeaxanthin, and ω-3 on Macular Pigment: A Randomized Clinical Trial,” by Korobelnik et al1 has drawn conclusions that may not follow readily from the data. In specific, the finding that macular pigment (MP) does not increase in response to supplemental lutein among first-generation offspring of patients with neovascular age-related macular degeneration (AMD) might not be correct.
Beatty S, Power R, Nolan J. Questioning Macular Pigment Measurement Methods and Genetic Risk of Age-Related Macular Degeneration. JAMA Ophthalmol. 2018;136(4):453. doi:10.1001/jamaophthalmol.2018.0326
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