Liu et al1 examined the effects of
intravitreal corticosteroid and antibiotic administration in the treatment
of Bacillus cereus endophthalmitis. The authors concluded
that combination therapy decreased anterior segment inflammation and was beneficial
to the retina compared with antibiotic treatment alone. The use of intravitreal
steroids to treat bacterial endophthalmitis is controversial because of contradicting
reports on the benefits of combination therapy during infection. Although
the authors cited several supporting reports, many studies reporting either
no overall benefit2-5
or harmful effects6 of intravitreal steroid
and antibiotic treatment were not cited.
Callegan MC, Parke DW, Gilmore MS. Corticosteroid and Antibiotic Therapy for Bacillus Endophthalmitis. Arch Ophthalmol. 2001;119(9):1391–1392. doi:
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