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September 2001

Corticosteroid and Antibiotic Therapy for Bacillus Endophthalmitis

Arch Ophthalmol. 2001;119(9):1391-1392. doi:

Liu et al1 examined the effects of intravitreal corticosteroid and antibiotic administration in the treatment of Bacillus cereus endophthalmitis. The authors concluded that combination therapy decreased anterior segment inflammation and was beneficial to the retina compared with antibiotic treatment alone. The use of intravitreal steroids to treat bacterial endophthalmitis is controversial because of contradicting reports on the benefits of combination therapy during infection. Although the authors cited several supporting reports, many studies reporting either no overall benefit2-5 or harmful effects6 of intravitreal steroid and antibiotic treatment were not cited.

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