In this issue of JAMA Ophthalmology, Snyder et al1 report the association of cilioretinal artery with both the prevalence and incidence of late age-related macular degeneration (AMD) in the Age-Related Eye Disease Study. The investigators found that the presence of cilioretinal artery detected by baseline color fundus photographs was associated with a statistically significant reduction in both the prevalence and incidence of neovascular AMD in analyses of 3647 study participants. For those with cilioretinal artery, the prevalent cases had a lower baseline AMD severity score than those participants without cilioretinal artery. However, the mean change in progression of the AMD severity score was not significantly different at 5 years. There were also no statistically significant differences between eyes with or without cilioretinal artery for both prevalent and incident central geographic atrophy associated with AMD.
Chew EY. The Cilioretinal Artery—A Friend to Age-Related Macular Degeneration? JAMA Ophthalmol. 2018;136(9):1015–1016. doi:10.1001/jamaophthalmol.2018.2644
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