In this issue of JAMA Ophthalmology, Nguyen and colleagues1 provide a well-analyzed case-control series with 5-year outcomes of trabeculectomy in 135 eyes of 105 patients of African descent and 135 eyes of 117 patients of European descent. The authors concluded that the surgery was less successful in those of African descent, especially when analyzed by the proportions of patients achieving a final intraocular pressure (IOP) of 15 mm Hg or less or 12 mm Hg or less and control without the need for supplemental medical therapy. Patients of African descent were also more likely to have an early or late bleb leak. Nguyen et al1 suggested that their results justify considering new approaches to controlling wound healing in surgery in patients of African descent and also consideration of using nonfiltering operations.
Palmberg P. Determining If Race Should Be Considered Within the Choice of Glaucoma Surgery. JAMA Ophthalmol. 2018;136(10):1113–1114. doi:10.1001/jamaophthalmol.2018.2886
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