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Photo Essay
December 2001

Bilateral Multiple Eyelid Apocrine Hidrocystomas and Ectodermal Dysplasia

Arch Ophthalmol. 2001;119(12):1866-1867. doi:10.1001/archopht.119.12.1866

WHEN SEEN by us a 55-year-old woman and her 53-year-old brother were noted to have bilateral multiple eyelid cysts, which measured 1 to 3 mm (Figure 1), that they reported as first apparent during their early 20s. Both had palmoplantar hyperkeratosis (Figure 2). The fingernails and toenails were brittle, furrowed, and spooned (Figure 3). Both of the subjects were edentulous (Figure 4), their hair was sparse and fine, and they had scanty eyelashes and eyebrows. The sister had decreased salivary gland secretion and vaginal dryness, whereas the brother experienced excessive sweating and had undergone bilateral stellate sympathectomies. They were progeny of a nonconsanguineous marriage with no other affected family members.