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January 2002

Treating Subretinal Hemorrhage With Tissue Plasminogen Activator

Arch Ophthalmol. 2002;120(1):103. doi:

In reply

We thank Dr Hesse for his insightful comments. In our study, the supplier of tPA was Genentech Inc, San Francisco, Calif (the commercial name is Activase), and the tPA was diluted in sterile balanced salt solution (Alcon Laboratories, Ft Worth, Tex). A 30-gauge needle on a tuberculin syringe was used to inject a 0.1 to 0.2 mL dose of tPA. The concentration of tPA was either 20 µg/mL or 30 µg/mL, depending on the physician who ordered the tPA. The dose recorded in the table represents what the physician estimated to be the true dose injected into the vitreous.

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