In Reply We thank Abdulhussein et al for reading our article1 and for their comments. We would also like to thank the editors for the opportunity to reply.
We chose to use the term overdiagnosis in our study rather than the term misdiagnosis, because we were interested in analyzing all patients referred to us with a diagnosis of optic neuritis. This subsequently allowed us to identify factors that were more likely to correspond with a true diagnosis of optic neuritis (eg, an age younger than 50 years and the presence of an afferent pupillary defect) in addition to other factors that may have led to an inaccurate initial diagnosis.
Stunkel L, Kung NH, Van Stavern GP. Incidence and Causes of Overdiagnosis of Optic Neuritis: Physician Insecurity—Reply. JAMA Ophthalmol. 2018;136(11):1312–1313. doi:10.1001/jamaophthalmol.2018.3485
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