To the Editor We read with great interest the article by Dalvin et al1 concerning the association between myotonic dystrophy (DM1) and uveal melanoma. Recent evidence has shown that uveal melanoma is associated with mutations in genes responsible for the eye colors, with a higher disease prevalence in individuals with lighter-colored eyes.2 We agree with the authors on the importance of an accurate ophthalmic examination in patients with DM1, because they may present with many ophthalmic diseases across the life span. However, we believe it is important to put their findings into context with other large studies.
Rosa N, De Bernardo M, Politano L. Clarification on Uveal Melanoma Associated With Myotonic Dystrophy. JAMA Ophthalmol. 2018;136(12):1425–1426. doi:10.1001/jamaophthalmol.2018.4053
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