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JAMA Ophthalmology Clinical Challenge
December 2018

Recurrent Bilateral Periorbital Swelling

Author Affiliations
  • 1University of California, Davis, Eye Center, Sacramento
JAMA Ophthalmol. 2018;136(12):1406-1407. doi:10.1001/jamaophthalmol.2018.1856

A 47-year old woman with a history of adult-onset asthma and waxing and waning bilateral swelling of the upper eyelids presented with greater swelling of the left than right upper eyelids with yellow lesions (Figure 1A). Previous episodes had been treated successfully with oral prednisone, and the patient had numerous recurrences within the past 10 years. According to the patient’s report, a biopsy was performed several years ago at an outside institution, and the diagnosis was xanthelasma. She denied visual changes.

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