The image depicts a 60-year-old woman with bilateral cataracts and no history of amblyopia, strabismus, or systemic diseases. Color slitlamp photography of the left eye (Figure, A) showed a persistent pupillary membrane, with multiple iris strands extending from collarette to collarette and adhering to the anterior lens surface. Anterior segment optical coherence tomography angiography (Figure, B) showed vessels originating from the lesser arterial circle of the iris and anastomosing with one another centrally. Persistent pupillary membrane results from incomplete involution of the tunica vasculosa lentis, which supplies the epithelium of the lens during fetal development.1
Kadomoto S, Uji A, Tsujikawa A. Anterior Segment Optical Coherence Tomography Angiography in a Patient With Persistent Pupillary Membrane. JAMA Ophthalmol. 2018;136(11):e182932. doi:10.1001/jamaophthalmol.2018.2932
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: