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JAMA Ophthalmology Clinical Challenge
January 2019

Middle-aged Man With Bilateral Subretinal Fluid

Author Affiliations
  • 1Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston
  • 2Retina Consultants of Worcester, Worcester, Massachusetts
JAMA Ophthalmol. 2019;137(1):105-106. doi:10.1001/jamaophthalmol.2018.2759

A man in his mid-50s presented with painless blurry vision in the left eye. According to the patient’s report, he had experienced this vision abnormality in the left eye for 1 week. At presentation, visual acuity was 20/20 OD and 20/400 OS. Results of a dilated fundus examination were normal in the right eye and notable for a macular serous retinal detachment in the left eye (Figure 1A). Findings on optical coherence tomography (OCT) showed a dome-shaped collection of subretinal fluid in the macula (not shown). Late-phase fluorescein angiography revealed multifocal pinpoint areas of hyperfluorescence with mild leakage within the area of detachment (Figure 1B).

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