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Invited Commentary
December 6, 2018

Association Between Noninfectious Uveitis and Psychological Stress and the Importance of Holistic Management: Treating the Patient With Uveitis as an Individual—Not a Disease

Author Affiliations
  • 1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
  • 2Ministry of Health Holdings, Singapore
  • 3School of Medicine, National University of Singapore, Singapore
JAMA Ophthalmol. 2019;137(2):206-207. doi:10.1001/jamaophthalmol.2018.5910

In this issue of JAMA Ophthalmology, Berlinberg et al1 report a cross-sectional description of psychological stress in patients with noninfectious uveitis. Overall, noninfectious uveitis was found to be associated with greater psychological stress on subjective measurement via the Cohen 10-item Perceived Stress Scale, although this finding was not reproduced with objective measures of diurnal cortisol levels. These results emphasize the need for proactive assessment and management of psychological stress in patients with uveitis. However, as highlighted by the authors, the cross-sectional design precludes determination of whether psychological stress may be a cause or effect of uveitis in these patients.