A man in his mid-50s presented with reports of bilateral central ring scotomata of 2 months’ duration after ingestion of liquid sildenafil. He reports he consumed the entire 30-mL bottle (total dose, 750 mg, almost 10 times the recommended dose of 80 mg) and experienced debilitating night blindness, photophobia, and central doughnut-shaped field defects in both eyes. The nyctalopia and photophobia improved within days, but central ring scotomata persisted. He was a frequent sildenafil user prior to this episode and noted transient photophobia with sildenafil use in the past.
Brader HS, Athappilly GK, Loewenstein J. Retinal Toxicity Associated With Excessive Sildenafil Ingestion. JAMA Ophthalmol. Published online January 10, 2019. doi:10.1001/jamaophthalmol.2018.3652
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