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Photo Essay
October 2002

Epibulbar Nodule as a Symptom of Langerhans Cell Histiocytosis

Arch Ophthalmol. 2002;120(10):1400-1401. doi:10.1001/archopht.120.10.1400

A 6-YEAR-OLD BOY sought treatment with a yellowish-white cystic epibulbar nodule (Figure 1), white gingival lesions (Figure 2), and cervical lymphadenopathy. Histological examination of the nodule revealed eosinophilic granuloma (Figure 3) with positive CD1a antibody staining for Langerhans cell histiocytosis (Figure 4). Magnetic resonance imaging of the brain demonstrated mastoid bone infiltration. Chemotherapy and radiation therapy were performed.

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