A 5-year-old girl received a diagnosis of incontinentia pigmenti by skin biopsy results. Her best-corrected visual acuity was 20/32 OD. Fluorescein angiography showed nonperfusion and leakage from neovascularization (NV) in the temporal peripheral retina in that eye. Optical coherence tomography (OCT) angiography results showed foveal NV and parafoveal capillary nonperfusion (Figure). Another OCT image demonstrated inner retinal thinning that corresponded to the region of parafoveal capillary nonperfusion. Scatter laser photocoagulation was applied to the peripheral nonperfusion areas of the retina.
Tanaka S, Yokoi T, Azuma N. Foveal Neovascularization Detected by Optical Coherence Tomography Angiography in Incontinentia Pigmenti. JAMA Ophthalmol. 2019;137(3):e184197. doi:10.1001/jamaophthalmol.2018.4197
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