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November 2002

High-Dose Supplements for Age-Related Macular Degeneration: Did You Leave Out Centrum?

Arch Ophthalmol. 2002;120(11):1602. doi:

We read with interest the excellent study in the October 2001 issue of the ARCHIVES.1 The title and conclusions are quite specific that supplementation with vitamin C (500 mg), vitamin E (400 IU), and beta carotene (15 mg) with zinc oxide (80 mg) should be considered for patients with extensive intermediate-size drusen, at least 1 large druse, noncentral geographic atrophy in 1 or both eyes, or advanced age-related macular degeneration (AMD) or vision loss caused by AMD in 1 eye (without contraindications, such as smoking).

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