A 92-year-old man presented with a mass over his right eyebrow that grew in size over the course of 7 months. The lesion was hornlike and rubbery, with an erythematous base, and was 35 × 15 × 9 mm (Figure, A). Because of concern about a malignant condition, an excision was recommended and performed. Pathological test results revealed soft tissue lined by a hyperkeratotic, acanthotic squamous epithelium with considerable acute and chronic inflammation (Figure, B). Mild epithelial dysplasia in the setting of chronic inflammation was seen. A diagnosis of an inflamed verrucous keratosis was made. The patient recovered well, and at 3 months postoperation, the mass had not recurred.
Shafer BM, Lee V, Mehta S. Excision of a Large Cutaneous Horn. JAMA Ophthalmol. 2019;137(8):e185792. doi:10.1001/jamaophthalmol.2018.5792
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