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Ophthalmic Images
October 10, 2019

Angioid Streaks and Other Retinopathy in Pseudoxanthoma Elasticum

Author Affiliations
  • 1Department of Ophthalmology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan
JAMA Ophthalmol. 2019;137(10):e193129. doi:10.1001/jamaophthalmol.2019.3129

A 23-year-old woman with 20/20 visual acuity was referred for incidental ophthalmoscopic findings. Ophthalmoscopy results (Figure) showed a peau d'orange pattern of diffuse mottling of the outer retina demonstrating dark spots on a normal-appearing fundus, angioid streaks, peripapillary comet lesions, and a peripheral comet rain in both eyes. She received a diagnosis of pseudoxanthoma elasticum (PXE) after undergoing a skin biopsy.

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