To the Editor Ismail et al1 determined the strength of the association between dry eye disease (DED) and migraine headaches in patients at health care facilities affiliated with the University of North Carolina. The crude odds ratio of migraines was 1.72 (95% CI, 1.60-1.85), and the adjusted odds ratio was 1.42 (95% CI, 1.20-1.68).1
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Kostev K. Association Between Migraine Headaches and Dry Eye Disease in Patients Studied in General Practices in Germany. JAMA Ophthalmol. 2020;138(2):223. doi:10.1001/jamaophthalmol.2019.5106
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