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Invited Commentary
February 6, 2020

Association Between Visit Adherence and Visual Acuity in Neovascular Age-Related Macular Degeneration

Author Affiliations
  • 1Vanderbilt Eye Institute, Nashville, Tennessee
  • 2Vanderbilt Medical Group, School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
JAMA Ophthalmol. Published online February 6, 2020. doi:10.1001/jamaophthalmol.2019.4644

The secondary analysis of Comparison of Age-Related Macular Degeneration Treatment Trial (CATT)1 data performed by Ramakrishnan et al2 in this issue of JAMA Ophthalmology investigates the association between visit adherence and visual acuity in individuals with neovascular age-related macular degeneration (AMD). Anti–vascular endothelial growth factor injections have introduced a paradigm shift in how ophthalmologists treat patients with neovascular AMD. However, these treatments come at considerable costs, including the treatment burden on patients. Frequent office visits place stress on a patient population that includes elderly individuals and individuals with visual impairments, leading to missed visits and loss to follow-up. The authors set out to better understand the association between office-visit adherence and visual outcomes in patients receiving anti–vascular endothelial growth factor therapy for neovascular AMD.

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