[Skip to Navigation]
Views 3,354
Citations 0
JAMA Ophthalmology Clinical Challenge
February 13, 2020

A Mysterious Central Scotoma in a Teenage Male Patient

Author Affiliations
  • 1Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago
  • 2Division of Ophthalmology, NorthShore University HealthSystem, Evanston, Illinois
  • 3Pritzker School of Medicine, The University of Chicago, Chicago, Illinois
JAMA Ophthalmol. 2020;138(4):414-415. doi:10.1001/jamaophthalmol.2019.5383

A white teenage boy was referred for 3 months of bilateral reduced central visual acuity characterized as atraumatic, painless, constant, symmetric, and nonprogressive. His parents reported that he had recently been hospitalized for a suspected overdose with the medications atomoxetine, quetiapine, melatonin, fluoxetine, bupropion, and clonazepam, and shortly after, he reported central visual acuity loss. A dilated fundus examination with normal results had been documented 6 months prior to our examination.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words