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JAMA Ophthalmology Clinical Challenge
April 16, 2020

Homonymous Hemianopia With Normal Magnetic Resonance Imaging

Author Affiliations
  • 1Wilmer Eye Institute, Division of Neuro-Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 2Department of Ophthalmology, Duke Eye Center, Durham, North Carolina
  • 3Royal College of Surgeons in Ireland, Dublin, Ireland
JAMA Ophthalmol. 2020;138(6):702-703. doi:10.1001/jamaophthalmol.2020.0447
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    1 Comment for this article
    Homonymous Hemianopia With Normal Magnetic Resonance Imaging
    Narayanaswamy Venketasubramanian, MB,BS | Raffles Neuroscience Centre, Raffles Hospital, Singapore
    Thank you for this very illustrative case. May I ask if the MRI brain included DWI sequences?, as it may show increased occipital cortical ribboning in this CJD variant.

    Thank you again


    1. Kallenberg K, Schulz-Schaeffer WJ, Jastrow U, Poser S, Meissner B, Tschampa
    HJ, Zerr I, Knauth M. Creutzfeldt-Jakob disease: comparative analysis of MR
    imaging sequences. AJNR Am J Neuroradiol. 2006 Aug;27(7):1459-62.

    2. Young GS, Geschwind MD, Fischbein NJ, Martindale JL, Henry RG, Liu S, Lu Y,
    Wong S, Liu H, Miller BL, Dillon WP. Diffusion-weighted and fluid-attenuated
    inversion recovery imaging in Creutzfeldt-Jakob disease:
    high sensitivity and
    specificity for diagnosis. AJNR Am J Neuroradiol. 2005 Jun-Jul;26(6):1551-62.

    3. Mendez OE, Shang J, Jungreis CA, Kaufer DI. Diffusion-weighted MRI in
    Creutzfeldt-Jakob disease: a better diagnostic marker than CSF protein 14-3-3? J
    Neuroimaging. 2003 Apr;13(2):147-51.

    4. Parker SE, Gujrati M, Pula JH, Zallek SN, Kattah JC. The heidenhain variant of
    Creutzfeldt-Jakob disease--a case series. J Neuroophthalmol. 2014 Mar;34(1):4-9.