To the Editor Siedlecki et al1 compared dark (DC) and milk chocolate (MC) consumption on optical coherence tomography angiography (OCT-A), visual acuity (VA), and large-letter contrast sensitivity.1 Their study was based on Rabin et al,2 comparing DC with MC on VA, large-letter CS, and small-letter CS (SLCS). While both studies reported minimal VA and large-letter CS effects, Rabin et al2 reported improved SLCS possibly because of flavanol-associated increased blood flow, suggesting that SLCS can identify visual acuity changes despite normal VA.3 The well-executed Siedlecki et al1 study included double masking, baseline measures, and OCT-A. However, we raise questions and offer comments.
Rabin JC, Carvalho P, Franklin CE. Questions on a Study on the Effects of Flavanol-Rich Dark Chocolate on Visual Function and Retinal Perfusion. JAMA Ophthalmol. 2020;138(7):799. doi:10.1001/jamaophthalmol.2020.1487
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.