Mitogen-activated protein kinase (MAPK) kinase (MEK) inhibitor–associated retinopathy (MEKAR) is typically associated with isolated, self-limited serous retinal detachment.1,2 Here, we report what is, to our knowledge, the first case of extracellular signal-regulated kinase (ERK) inhibitor–associated retinopathy (ERKAR), following treatment with a first-in-class ERK1/ERK2 inhibitor BVD523 (ulixertinib).
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Sioufi K, Das S, Say EAT. A Case of Extracellular Signal-Regulated Kinase Inhibitor–Associated Retinopathy. JAMA Ophthalmol. Published online July 30, 2020. doi:10.1001/jamaophthalmol.2020.2716
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